<div dir="ltr"><div class="gmail_default" style="font-family:verdana,sans-serif;font-size:small">From Merck Manual: (This is only 3 of the dozen or so bleeding disorders mentioned on the Merck website. I am sure the actual manual goes into more detail</div>
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<div><font size="4">'<strong>Canine thrombopathia</strong> has been reported in Basset Hounds. Affected dogs have nosebleeds, tiny purplish red spots, and bleeding of the gums. This disorder should be suspected in Basset Hounds that have these signs, along with normal levels of platelets and von Willebrand's factor. Specific diagnosis of this disorder requires specialized platelet function testing. There is no specific treatment, but in cases of severe bleeding, plasma or whole blood transfusions may be needed.<a name="v3201061"></a> <p>
<b>Thrombasthenic thrombopathia</b> has been diagnosed in Otterhounds. Affected dogs have prolonged bleeding times and form large bruises easily. A large number of oddly shaped, giant platelets are seen in blood tests. Platelets from dogs with this disorder do not clump together or separate as they normally should. There is no specific treatment. In cases of severe bleeding, transfusions of plasma or whole blood can be given.</p>
<a name="v3201062"></a> <p><b>Von Willebrand's disease</b> is caused by a defective or deficient von Willebrand's factor. Von Willebrand's factor is the protein that carries an important clotting factor (Factor VIII) in the blood and that regulates the first step in clot formation. It is the most common inherited bleeding disorder in dogs and occurs in nearly all breeds and in mixed breeds. The disorder is most common in Doberman Pinschers, German Shepherds, Golden Retrievers, Miniature Schnauzers, Pembroke Welsh Corgis, Shetland Sheepdogs, Basset Hounds, Scottish Terriers, Standard Poodles, and Standard Manchester Terriers.</p>
<a name="v3201064"></a> <p>Two types of the disease are known. In the less common form, the condition is either deadly, or results in the dog being a carrier that has no symptoms. In the more common form, the dog can have bleeding of the gums, nosebleeds, and blood in the urine. Some puppies may bleed excessively only after injection or surgery. Signs of von Willebrand's disease are similar to those of platelet disorders. Laboratory tests are required to confirm the diagnosis. Treatment requires transfusion with whole blood or plasma.</p>
<p><br></p><p><div class="gmail_default" style="font-family:verdana,sans-serif;font-size:small;display:inline">MomPerson to Nigel, Llewis, Conley & Doc</div><p></p></p></font></div></div>
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