[Dailydrool] Bleeding disorders

[Beverly Szaton]

>From Merck Manual: (This is only 3 of the dozen or so bleeding disorders
mentioned on the Merck website. I am sure the actual manual goes into more
detail



-- 
'*Canine thrombopathia* has been reported in Basset Hounds. Affected dogs
have nosebleeds, tiny purplish red spots, and bleeding of the gums. This
disorder should be suspected in Basset Hounds that have these signs, along
with normal levels of platelets and von Willebrand's factor. Specific
diagnosis of this disorder requires specialized platelet function testing.
There is no specific treatment, but in cases of severe bleeding, plasma or
whole blood transfusions may be needed.

*Thrombasthenic thrombopathia* has been diagnosed in Otterhounds. Affected
dogs have prolonged bleeding times and form large bruises easily. A large
number of oddly shaped, giant platelets are seen in blood tests. Platelets
from dogs with this disorder do not clump together or separate as they
normally should. There is no specific treatment. In cases of severe
bleeding, transfusions of plasma or whole blood can be given.

*Von Willebrand's disease* is caused by a defective or deficient von
Willebrand's factor. Von Willebrand's factor is the protein that carries an
important clotting factor (Factor VIII) in the blood and that regulates the
first step in clot formation. It is the most common inherited bleeding
disorder in dogs and occurs in nearly all breeds and in mixed breeds. The
disorder is most common in Doberman Pinschers, German Shepherds, Golden
Retrievers, Miniature Schnauzers, Pembroke Welsh Corgis, Shetland
Sheepdogs, Basset Hounds, Scottish Terriers, Standard Poodles, and Standard
Manchester Terriers.

Two types of the disease are known. In the less common form, the condition
is either deadly, or results in the dog being a carrier that has no
symptoms. In the more common form, the dog can have bleeding of the gums,
nosebleeds, and blood in the urine. Some puppies may bleed excessively only
after injection or surgery. Signs of von Willebrand's disease are similar
to those of platelet disorders. Laboratory tests are required to confirm
the diagnosis. Treatment requires transfusion with whole blood or plasma.


​MomPerson to Nigel, Llewis, Conley & Doc
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